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Senoo, Dodzi Kwaku Jnr., Acton, Luke and Hall, Lindsay J. 
ORCID: https://orcid.org/0000-0001-8938-5709
(2026)
From diet to function: using synthetic microbial communities to map gut microbial interactions.
npj Biofilms and Microbiomes, 12 (1).
ISSN 2055-5008
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Abstract
Diet shapes gut microbial ecology and function, but causal mechanisms are hard to resolve in native communities. Synthetic microbial communities provide defined systems to test how dietary substrates alter community structure, metabolism, and host responses. This review summarises SynCom design, experimental platforms, and dietary applications, highlights multi-omics and modelling approaches, proposes reporting standards, and considers challenges and future directions, including multi-kingdom and AI-enabled function-first SynComs.
| Item Type: | Article |
|---|---|
| Additional Information: | Data availability: No datasets were generated or analysed during the current study. |
| Uncontrolled Keywords: | biotechnology,microbiology,applied microbiology and biotechnology ,/dk/atira/pure/subjectarea/asjc/1300/1305 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 13 Oct 2026 09:22 |
| Last Modified: | 13 Oct 2026 09:37 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/104765 |
| DOI: | 10.1038/s41522-026-01012-9 |
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