Tools
ToolsENIGMA-Epilepsy Working Group (2020) The ENIGMA‐Epilepsy working group: Mapping disease from large data sets. Human Brain Mapping, 43 (1). ISSN 1065-9471
Preview |
PDF (Human Brain Mapping - 2020 - Sisodiya - The ENIGMA‐Epilepsy working group Mapping disease from large data sets)
- Published Version
Available under License Creative Commons Attribution. Download (6MB) | Preview |
Abstract
Epilepsy is a common and serious neurological disorder, with many different constituent conditions characterized by their electro clinical, imaging, and genetic features. MRI has been fundamental in advancing our understanding of brain processes in the epilepsies. Smaller‐scale studies have identified many interesting imaging phenomena, with implications both for understanding pathophysiology and improving clinical care. Through the infrastructure and concepts now well‐established by the ENIGMA Consortium, ENIGMA‐Epilepsy was established to strengthen epilepsy neuroscience by greatly increasing sample sizes, leveraging ideas and methods established in other ENIGMA projects, and generating a body of collaborating scientists and clinicians to drive forward robust research. Here we review published, current, and future projects, that include structural MRI, diffusion tensor imaging (DTI), and resting state functional MRI (rsfMRI), and that employ advanced methods including structural covariance, and event‐based modeling analysis. We explore age of onset‐ and duration‐related features, as well as phenomena‐specific work focusing on particular epilepsy syndromes or phenotypes, multimodal analyses focused on understanding the biology of disease progression, and deep learning approaches. We encourage groups who may be interested in participating to make contact to further grow and develop ENIGMA‐Epilepsy.
| Item Type: | Article |
|---|---|
| Additional Information: | Data Availability Statement: Data sharing is not applicable to this article as no new data were created or analyzed in this study. |
| Faculty \ School: | Faculty of Social Sciences > School of Psychology |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 24 Sep 2026 14:45 |
| Last Modified: | 24 Sep 2026 19:01 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/104634 |
| DOI: | 10.1002/hbm.25037 |
Downloads
Downloads per month over past year
Actions (login required)
 |
View Item |