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Khan, Khuzaima, Amir, Eiman, Akano, Omobolaji, Borucki, Joseph, Al Thaher, Ahmad, Stather, Philip 
ORCID: https://orcid.org/0000-0002-3585-6728 and Ali, Tariq
(2025)
Challenging the Controversy Surrounding Percutaneous Brachial Artery Access Related Complications:A Systematic Review and Meta-Analysis.
Vascular and Endovascular Surgery, 59 (1).
pp. 47-63.
ISSN 1538-5744
Abstract
Background: Endovascular therapy has become increasingly preferred in the diagnosis and treatment of various conditions. The choice of arterial access usually depends on the type of procedure being performed with most via the common femoral artery and increasingly via the radial artery. Percutaneous access via the brachial artery has however been approached with caution due to the perceived increased risk for development of complications. Percutaneous brachial artery access (pBAA) has insufficient evidence when compared to femoral and radial access, with no large-scale studies available. The objective of this study is to review the literature and report the clinical and radiological complications associated with pBAA. Methods: EMBASE, EMCARE, CINAHL and Medline were searched for existing data on the complications associated with pBAA. Systematic review and meta-analysis were carried out on the data of 31 studies. Results: The results of this systematic review and meta-analysis indicates that the probability of post procedural haematoma was 4.76%, haemorrhage 1.43%, perforation 1.11% pseudoaneurysm 1.06%, spasm 0.9%, thrombus 0.55%, neuropathy 0.53%, occlusion 0.51%, ischaemia 0.37% and infection 0.24 %. Non-target vessel puncture, stenosis and stroke had a 0% incidence among the assessed population. Conclusion: This study provides evidence to support clinical decision making when it comes to the utility of pBAA in endovascular diagnosis or therapy. The results demonstrate that pBAA is relatively safe with a low incidence of serious complications and thereby provide the clinician with the option of an alternate access point when planning treatment.
| Item Type: | Article |
|---|---|
| Additional Information: | Acknowledgements Thanks to John Losasso of the Norfolk and Norwich University Hospital Library for his help with our literature search. |
| Uncontrolled Keywords: | brachial artery,complications,percutaneous arterial access,vascular access,surgery,cardiology and cardiovascular medicine ,/dk/atira/pure/subjectarea/asjc/2700/2746 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 04 Sep 2026 14:38 |
| Last Modified: | 06 Sep 2026 05:28 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/104432 |
| DOI: | 10.1177/15385744241278048 |
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