Therapeutic advances in the management of chronic hepatitis B infection

Brooks, Johanne, Gelson, William and Rushbrook, Simon M. (2013) Therapeutic advances in the management of chronic hepatitis B infection. Therapeutic Advances in Chronic Disease, 4 (4). pp. 157-166. ISSN 2040-6223

Full text not available from this repository. (Request a copy)

Abstract

Hepatitis B virus (HBV) is a small nonenveloped DNA virus that is a member of the Hepadnaviridae family. Chronic HBV infection is estimated to effect more than 350 million people worldwide with over 2 billion people being exposed to the virus. Risk factors for chronic infection include age of exposure to the virus, concurrent immunosuppression and HIV infection. Individuals chronically infected are 200 times more likely to develop hepatocellular carcinoma (HCC) than uninfected individuals and are at risk of developing cirrhosis and the risks of decompensated liver disease. This article focuses on the recent therapeutic advances that reduce the risk of developing these complications, those that prevent the spread of HBV and strategies for the prevention of post-liver-transplantation recurrence of HBV.

Item Type:	Article
Uncontrolled Keywords:	chronic infection,hepatitis b,treatment,medicine (miscellaneous) ,/dk/atira/pure/subjectarea/asjc/2700/2701
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
Related URLs:	https://www.scopus.com/pages/publication...
Depositing User:	LivePure Connector
Date Deposited:	30 Jun 2026 13:41
Last Modified:	30 Jun 2026 15:24
URI:	https://ueaeprints.uea.ac.uk/id/eprint/103550
DOI:	10.1177/2040622313484647

Actions (login required)

View Item