Treatment of Diabetic Ketoacidosis (DKA)/Hyperglycemic Hyperosmolar State (HHS): Novel Advances in the Management of Hyperglycemic Crises (UK Versus USA)

Dhatariya, Ketan K. and Vellanki, Priyathama (2017) Treatment of Diabetic Ketoacidosis (DKA)/Hyperglycemic Hyperosmolar State (HHS): Novel Advances in the Management of Hyperglycemic Crises (UK Versus USA). Current Diabetes Reports, 17 (5). ISSN 1534-4827

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    Abstract

    Purpose of Review: Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are diabetic emergencies that cause high morbidity and mortality. Their treatment differs in the UK and USA. This review delineates the differences in diagnosis and treatment between the two countries. Recent Findings: Large-scale studies to determine optimal management of DKA and HHS are lacking. The diagnosis of DKA is based on disease severity in the USA, which differs from the UK. The diagnosis of HHS in the USA is based on total rather than effective osmolality. Unlike the USA, the UK has separate guidelines for DKA and HHS. Treatment of DKA and HHS also differs with respect to timing of fluid and insulin initiation. Summary: There is considerable overlap but important differences between the UK and USA guidelines for the management of DKA and HHS. Further research needs to be done to delineate a unifying diagnostic and treatment protocol.

    Item Type: Article
    Uncontrolled Keywords: diabetic ketoacidosis,management,survey,hyperglycemic hyperosmolar state
    Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
    University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Clinical Science and Trials
    Related URLs:
    Depositing User: Pure Connector
    Date Deposited: 27 Apr 2017 06:50
    Last Modified: 25 Jul 2018 13:32
    URI: https://ueaeprints.uea.ac.uk/id/eprint/63312
    DOI: 10.1007/s11892-017-0857-4

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