Position Paper on Olfactory Dysfunction

Hummel, T, Whitcroft, KL, Andrews, P, Altundag, A, Cinghi, C, Costanzo, RM, Damm, M, Frasnelli, J, Gudziol, H, Gupta, N, Haehner, A, Holbrook, E, Hong, SC, Hornung, D, Hüttenbrink, KB, Kamel, R, Kobayashi, M, Konstantinidis, I, Landis, BN, Leopold, DA, Macchi, A, Miwa, T, Moesges, R, Mullol, J, Mueller, CA, Ottaviano, G, Passali, GC, Philpott, C, Pinto, JM, Ramakrishnan, VJ, Rombaux, P, Roth, Y, Schlosser, RA, Shu, B, Soler, G, Stjärne, P, Stuck, BA, Vodicka, J and Welge-Luessen, A (2017) Position Paper on Olfactory Dysfunction. Rhinology. Supplement, 54 (26). ISSN 1013-0047

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    Abstract

    Background: Olfactory dysfunction is an increasingly recognised condition, associated with reduced quality of life and major health outcomes such as neurodegeneration and death. However, translational research in this field is limited by heterogeneity in methodological approach, including definitions of impairment, improvement and appropriate assessment techniques. Accordingly, effective treatments are limited. In an effort to encourage high quality and comparable work in this field, among others, we propose the following ideas and recommendations. Whilst full recommendations are outlined in the main document, key points include: -Patients with suspected olfactory loss should undergo a full examination of the head and neck, including rigid nasal endoscopy. -Subjective olfactory assessment should not be undertaken in isolation, given its poor reliability. -Psychophysical assessment tools used in clinical and research settings should include reliable and validated tests of odour threshold, and/or one of odour identification or discrimination. -Comprehensive chemosensory assessment should include gustatory screening. -Smell training can be helpful in patients with olfactory loss of several aetiologies. Conclusions: We hope the current manuscript will encourage clinicians and researchers to adopt a common language, and in so doing, increase the methodological quality, consistency and generalisability of work in this field.

    Item Type: Article
    Uncontrolled Keywords: humans,neuropsychological tests,olfaction disorders,olfactometry,olfactory perception,quality of life,journal article,review,otorhinolaryngology ,/dk/atira/pure/subjectarea/asjc/2700/2733
    Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
    University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Clinical Science and Trials
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    Depositing User: Pure Connector
    Date Deposited: 31 Jan 2017 02:17
    Last Modified: 10 Aug 2018 12:30
    URI: https://ueaeprints.uea.ac.uk/id/eprint/62231
    DOI: 10.4193/Rhino16.248

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