Regulation of pattern recognition receptor signalling in plants

Silva Couto, Daniel and Zipfel, Cyril (2016) Regulation of pattern recognition receptor signalling in plants. Nature Reviews Immunology, 16 (9). 537–552. ISSN 1474-1733

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    Abstract

    Recognition of pathogen-derived molecules by pattern recognition receptors (PRRs) is a common feature of both animal and plant innate immune systems. In plants, PRR signalling is initiated at the cell surface by kinase complexes, resulting in the activation of immune responses that ward off microbes. However, the activation and amplitude of innate immune responses must be tightly controlled. In this Review, we summarize our knowledge of the early signalling events that follow PRR activation, and describe the mechanisms that fine-tune immune signalling to maintain immune homeostasis. We also illustrate the mechanisms used by pathogens to inhibit innate immune signalling, and discuss how the innate ability of plant cells to monitor the integrity of key immune components can lead to autoimmune phenotypes upon genetic or pathogen-induced perturbations of these components.

    Item Type: Article
    Faculty \ School: Faculty of Science > School of Biological Sciences
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    Depositing User: Pure Connector
    Date Deposited: 16 Jun 2016 16:00
    Last Modified: 09 Apr 2019 11:17
    URI: https://ueaeprints.uea.ac.uk/id/eprint/59377
    DOI: 10.1038/nri.2016.77

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