Synthesis of two 'heteroaromatic rings of the future' for applications in medicinal chemistry

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Silva Júnior, P. E., Rezende, L. C D, Gimenes, Julia Possamai, Maltarollo, Vinícius Goncąlves, Dale, James, Trossini, G. H G, Emery, F. S. and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2016) Synthesis of two 'heteroaromatic rings of the future' for applications in medicinal chemistry. RSC Advances, 6 (27). pp. 22777-22780. ISSN 2046-2069

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Abstract

In a computational study, the 1H-pyrazolo[3,4-c]pyridin-5-ol and 2,6-naphthyridin-3-ol heterocycles were identified as unknown heteroaromatic ring systems of potential value for medicinal chemistry. Here we report robust and concise synthetic protocols that provide access to these two scaffolds on a multigram scale.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Pharmacy
UEA Research Groups:	Faculty of Science > Research Groups > Medicinal Chemistry (former - to 2017) Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021)
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	Pure Connector
Date Deposited:	09 May 2016 15:00
Last Modified:	22 Oct 2022 01:02
URI:	https://ueaeprints.uea.ac.uk/id/eprint/58601
DOI:	10.1039/c6ra01099g

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