Tuning the spontaneous formation kinetics of caffeine:malonic acid co-crystals

Nartowski, Karol, Khimyak, Yaroslav ORCID: https://orcid.org/0000-0003-0424-4128 and Berry, David (2016) Tuning the spontaneous formation kinetics of caffeine:malonic acid co-crystals. CrystEngComm, 18 (15). pp. 2617-2620. ISSN 1466-8033

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Abstract

It has previously been reported that the caffeine : malonic acid co-crystal system forms spontaneously upon the contact of the two materials. Here we studied the crystal growth in this system to rationally define the role that water plays, thus enabling us to monitor the conversion by solid-state NMR and control the kinetics of spontaneous co-crystal production by increasing or decreasing the relative humidity.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy
Faculty of Science
UEA Research Groups: Faculty of Science > Research Groups > Drug Delivery and Pharmaceutical Materials (former - to 2017)
Faculty of Science > Research Groups > Pharmaceutical Materials and Soft Matter
Depositing User: Pure Connector
Date Deposited: 19 Apr 2016 12:00
Last Modified: 21 Mar 2024 01:12
URI: https://ueaeprints.uea.ac.uk/id/eprint/58305
DOI: 10.1039/C6CE00353B

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