Nutrition, diet and immunosenescence

Maijó, Mònica, Clements, Sarah J., Ivory, Kamal, Nicoletti, Claudio and Carding, Simon (2014) Nutrition, diet and immunosenescence. Mechanisms of Ageing and Development, 136-137. pp. 116-128. ISSN 0047-6374

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    Abstract

    Ageing is characterized by immunosenescence and the progressive decline in immunity in association with an increased frequency of infections and chronic disease. This complex process affects both the innate and adaptive immune systems with a progressive decline in most immune cell populations and defects in activation resulting in loss of function. Although host genetics and environmental factors, such as stress, exercise and diet can impact on the onset or course of immunosenescence, the mechanisms involved are largely unknown. This review focusses on identifying the most significant aspects of immunosenescence and on the evidence that nutritional intervention might delay this process, and consequently improve the quality of life of the elderly.

    Item Type: Article
    Uncontrolled Keywords: immunosenescence,ageing,nutrition
    Faculty \ School: Faculty of Science > School of Biological Sciences
    Faculty of Medicine and Health Sciences > Norwich Medical School
    University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
    Depositing User: Pure Connector
    Date Deposited: 01 Apr 2016 15:00
    Last Modified: 25 Jul 2018 11:58
    URI: https://ueaeprints.uea.ac.uk/id/eprint/58089
    DOI: 10.1016/j.mad.2013.12.003

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