19F NMR imaging of blood oxygenation in the brain

Eidelberg, D., Johnson, G., Barnes, D., Tofts, P. S., Delpy, D., Plummer, D. and McDonald, W. I. (1988) 19F NMR imaging of blood oxygenation in the brain. Magnetic Resonance in Medicine, 6 (3). pp. 344-352. ISSN 0740-3194

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Abstract

Perfluorocarbon (PFC) emulsions have been developed as oxygen carrying blood substitutes. High fluorine concentrations allow them to be used in 19F NMR imaging of blood vessels. Furthermore, 19F relaxation times in PFCs are dependent on oxygen tension (pO2) so that NMR imaging may provide a noninvasive method of measuring spatially localized pO2 values in vivo. Using these principles, we have formed 19F images and calculated pO2 maps of the cat brain.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 07 Oct 2015 15:00
Last Modified: 09 Oct 2017 22:08
URI: https://ueaeprints.uea.ac.uk/id/eprint/54603
DOI: 10.1002/mrm.1910060312

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