Genetic variation in myosin IXB is associated with ulcerative colitis

van Bodegraven, Adriaan A, Curley, Christine R, Hunt, Karen A, Monsuur, Alienke J, Linskens, Ronald K, Onnie, Clive M, Crusius, J Bart A, Annese, Vito, Latiano, Anna, Silverberg, Mark S, Bitton, Alain, Fisher, Sheila A, Steinhart, A Hilary, Forbes, Alastair, Sanderson, Jeremy, Prescott, Natalie J, Strachan, David P, Playford, Raymond J, Mathew, Christopher G, Wijmenga, Cisca, Daly, Mark J, Rioux, John D and van Heel, David A (2006) Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology, 131 (6). pp. 1768-74. ISSN 0016-5085

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Abstract

Common germline genetic variation in the 3' region of myosin IXB (MYO9B) has been associated recently with susceptibility to celiac disease, with a hypothesis that MYO9B variants might influence intestinal permeability. These findings suggested the current study investigating a possible further role for MYO9B variation in inflammatory bowel disease.

Item Type: Article
Uncontrolled Keywords: adolescent,adult,aged,aged, 80 and over,case-control studies,child,cohort studies,colitis, ulcerative,european continental ancestry group,female,genetic predisposition to disease,genetic variation,genotype,humans,male,middle aged,myosins,polymorphism, single nucleotide
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Nutrition
Depositing User: Pure Connector
Date Deposited: 06 Aug 2014 11:58
Last Modified: 23 Aug 2018 14:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/49671
DOI: 10.1053/j.gastro.2006.09.011

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