Foetal steroid binding protein and malignancy

Forbes, A (1987) Foetal steroid binding protein and malignancy. Anticancer Research, 7 (5B). pp. 937-41. ISSN 0250-7005

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Abstract

Foetal steroid binding protein (FSBP) is a normal constituent of adult human serum; in vivo it appears to influence the degree of steroid binding to albumin rather than acting primarily as a high affinity saturable binding protein. Serum levels are elevated in patients with parenchymal liver disease, hepatic malignancy and in those with non-metastatic breast cancer. That FSBP is protective against the development of breast carcinoma is however supported by a comparison of healthy women from racial groups at differing risk of this malignancy in which higher levels are found in those at lower risk. This hypothesis and the possible links between FSBP and primary hepatocellular carcinoma are further examined.

Item Type: Article
Uncontrolled Keywords: breast neoplasms,carcinoma, hepatocellular,carrier proteins,female,fetal proteins,humans,liver cirrhosis,liver neoplasms,male
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 06 Aug 2014 11:44
Last Modified: 11 Apr 2019 15:39
URI: https://ueaeprints.uea.ac.uk/id/eprint/49507
DOI:

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