Recombinant human gamma-interferon in primary hepatocellular carcinoma

Forbes, A, Johnson, P J and Williams, R (1985) Recombinant human gamma-interferon in primary hepatocellular carcinoma. Journal of the Royal Society of Medicine, 78 (10). pp. 826-9. ISSN 0141-0768

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Abstract

A phase II trial of recombinant human gamma-interferon in the treatment of unresectable primary hepatocellular carcinoma is reported. The trial was terminated prematurely after recruitment of only 7 patients because of unacceptable toxicity, predominantly renal. There was no evidence of response in any of the 7 patients but some evidence that disease progression was more rapid during the treatment period.

Item Type: Article
Uncontrolled Keywords: adult,carcinoma, hepatocellular,drug evaluation,female,humans,interferon-gamma,liver neoplasms,male,middle aged,time factors,alpha-fetoproteins
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Nutrition
Depositing User: Pure Connector
Date Deposited: 06 Aug 2014 11:44
Last Modified: 02 Aug 2018 15:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/49496
DOI:

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