The influence of cooked kidney beans (Phaseolus vulgaris) on intestinal cell turnover and faecal nitrogen excretion in the rat

Fairweather-Tait, S J, Gee, J M and Johnson, I T (1983) The influence of cooked kidney beans (Phaseolus vulgaris) on intestinal cell turnover and faecal nitrogen excretion in the rat. British Journal of Nutrition, 49 (3). pp. 303-312. ISSN 0007-1145

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Abstract

Male Wistar rats were fed on semi-synthetic diets containing cooked white kidney beans (Phaseolus vulgaris) or equivalent levels of protein and carbohydrate. No change was observed in over-all nitrogen balance in animals fed on the bean diet, but there was a two- to three-fold increase in their faecal excretion, compared with control rats. This was compensated by a decrease in urinary-N excretion. Homogenized small intestinal mucosa, prepared from bean-fed animals, showed a 28% increase in protein content compared with control material. Measurements of 3H-labelled thymidine turnover indicated that mucosal cell exfoliation was increased by approximately 35% in the small intestines of bean-fed rats compared with controls. It is concluded that though a diet rich in cooked P. vulgaris leads to some increase in mucosal cell turnover in the small intestine of rats, the consequent increase in mucosal protein loss could not account for the increased faecal-N excretion seen in these animals.

Item Type: Article
Uncontrolled Keywords: animals,cell count,diet,dietary proteins,fabaceae,feces,hot temperature,intestinal mucosa,intestine, small,male,nitrogen,plant proteins,plants, medicinal,proteins,rats,rats, inbred strains
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Nutrition
Faculty of Science > School of Biological Sciences
Depositing User: Pure Connector
Date Deposited: 06 Aug 2014 11:42
Last Modified: 25 Jul 2018 09:50
URI: https://ueaeprints.uea.ac.uk/id/eprint/49270
DOI: 10.1079/BJN19830039

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