True fractional calcium absorption in Chinese children measured with stable isotopes (42Ca and 44Ca)

Lee, W T, Leung, S S, Fairweather-Tait, S J, Leung, D M, Tsang, H S, Eagles, J, Fox, T, Wang, S H, Xu, Y C and Zeng, W P (1994) True fractional calcium absorption in Chinese children measured with stable isotopes (42Ca and 44Ca). British Journal of Nutrition, 72 (6). pp. 883-897. ISSN 0007-1145

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True fractional Ca absorption (TFCA) was compared in children with different habitual Ca intakes using a double-label stable-isotope technique. Chinese children aged 7 years from Hongkong (n22) and Jiangmen (n12) participated in the study. An oral administration of 8 mg 44Ca in 100 g chocolate milk was given shortly after an intravenous injection of 0.75 mg 42Ca. Ca isotopic ratios were determined in urine samples collected 24 h later using thermal-ionization mass spectrometry. There was no significant difference in TFCA between Jiangmen and Hongkong children (P = 0.16). TFCA of a lower-Ca-intake group (Ca 500 mg/d, n15) with mean Ca intake 862 mg/d was 54.8 (SD 7.3)%; the difference in TFCA was significant (P = 0.016). Serum levels of 25-hydroxycholecalciferol of the children were adequate (33.7 (SD 7.7) ng/ml). The present study indicates that growing children accustomed to a low-Ca diet appear to be able to enhance their absorptive capacity. If it is assumed that dietary Ca absorption by Chinese children resembles their TFCA from a single meal of chocolate milk, then the recommended dietary allowance (RDA) for Ca for Chinese children would be lower than the US RDA (800 mg/d), which is based on an estimated 40% Ca absorption as reported for Caucasian children. A comparative absorption study is necessary to determine whether there is any difference in TFCA between Caucasian and Chinese children.

Item Type: Article
Uncontrolled Keywords: body height,body weight,calcifediol,calcium,calcium isotopes,child,china,diet,female,humans,intestinal absorption,male,mass spectrometry
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Chemistry
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Faculty of Science > School of Environmental Sciences
Depositing User: Pure Connector
Date Deposited: 25 Jul 2014 13:42
Last Modified: 06 Dec 2018 16:30

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