Effect of calcium supplements and stage of lactation on the calcium absorption efficiency of lactating women accustomed to low calcium intakes

Fairweather-Tait, S, Prentice, A, Heumann, K G, Jarjou, L M, Stirling, D M, Wharf, S G and Turnlund, J R (1995) Effect of calcium supplements and stage of lactation on the calcium absorption efficiency of lactating women accustomed to low calcium intakes. American Journal of Clinical Nutrition, 62 (6). pp. 1188-92. ISSN 0002-9165

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Abstract

The effect of calcium intake on the calcium absorption efficiency from 100 mL cow milk was measured in lactating Gambian mothers habituated to a low-calcium diet [mean intake 7.08 mmol (283 mg)/d], and compared with UK lactating mothers consuming high-calcium diets [mean intake 29.2 mmol (1168 mg)/d] by using a double stable-isotope technique (oral 44Ca and intravenous 42Ca). In a double-blind trial starting 9 d postpartum, Gambian mothers were given a calcium supplement [17.85 mmol (714 mg)/d] or placebo for 12 mo. At 3 and 12 mo postpartum, mean (+/- SEM) calcium absorption from isotopically enriched milk was 52.3 +/- 3.1% (n = 25) and 47.2 +/- 4.8% (n = 24) in the unsupplemented Gambian mothers and 48.8 +/- 2.8% (n = 28) and 42.9 +/- 3.7% (n = 24) in the supplemented mothers, respectively. There was no effect of supplementation or stage of lactation on the efficiency of calcium absorption. At 3 mo postpartum the UK mothers absorbed 32.2 +/- 3.8% of the isotopically enriched calcium added to milk, which was significantly less than that of the Gambian mothers (P

Item Type: Article
Uncontrolled Keywords: absorption,administration, oral,adult,animals,calcium,calcium isotopes,calcium, dietary,dose-response relationship, drug,double-blind method,female,food, fortified,gambia,great britain,humans,injections, intravenous,lactation,mass spectrometry,milk
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 05 Aug 2014 13:30
Last Modified: 18 Sep 2018 12:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/49214
DOI:

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