Small RNA analysis in Sindbis virus infected human HEK293 cells

Donaszi-Ivanov, Andras, Mohorianu, Irina, Dalmay, Tamas and Powell, Penny P (2013) Small RNA analysis in Sindbis virus infected human HEK293 cells. PLoS ONE, 8 (12). ISSN 1932-6203

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    Abstract

    In contrast to the defence mechanism of RNA interference (RNAi) in plants and invertebrates, its role in the innate response to virus infection of mammals is a matter of debate. Since RNAi has a well-established role in controlling infection of the alphavirus Sindbis virus (SINV) in insects, we have used this virus to investigate the role of RNAi in SINV infection of human cells.

    Item Type: Article
    Additional Information: © 2013 Donaszi-Ivanov et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
    Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
    Faculty of Science > School of Biological Sciences
    University of East Anglia > Faculty of Science > Research Groups > Plant Sciences
    University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
    Depositing User: Pure Connector
    Date Deposited: 10 Jun 2014 21:28
    Last Modified: 25 Jul 2018 09:34
    URI: https://ueaeprints.uea.ac.uk/id/eprint/47879
    DOI: 10.1371/journal.pone.0084070

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