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Vaarhorst, Anika A M, Lu, Yingchang, Heijmans, Bastiaan T, Dollé, Martijn E T, Böhringer, Stefan, Putter, Hein, Imholz, Sandra, Merry, Audrey H H, van Greevenbroek, Marleen M, Jukema, J Wouter, Gorgels, Anton P M, van den Brandt, Piet A, Müller, Michael 
ORCID: https://orcid.org/0000-0002-5930-9905, Schouten, Leo J, Feskens, Edith J M, Boer, Jolanda M A and Slagboom, P Eline
(2012)
Literature-based genetic risk scores for coronary heart disease:the Cardiovascular Registry Maastricht (CAREMA) prospective cohort study.
Circulation: Cardiovascular Genetics, 5 (2).
pp. 202-209.
ISSN 1942-3268
Abstract
Genome-wide association studies (GWAS) have identified many single-nucleotide polymorphisms (SNPs) associated with coronary heart disease (CHD) or CHD risk factors (RF). Using a case-cohort study within the prospective Cardiovascular Registry Maastricht (CAREMA) cohort, we tested if genetic risk scores (GRS) based on GWAS-identified SNPs are associated with and predictive for future CHD.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | adult,cardiovascular diseases,female,follow-up studies,genome-wide association study,genotype,humans,male,middle aged,polymorphism, single nucleotide,prospective studies,registries,risk factors,young adult,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology |
| Depositing User: | Pure Connector |
| Date Deposited: | 10 Jun 2014 20:34 |
| Last Modified: | 24 Oct 2022 06:06 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/47658 |
| DOI: | 10.1161/CIRCGENETICS.111.960708 |
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