Age-related differences in signaling efficiency of human lens cells underpin differential wound healing response rates following cataract surgery

Dawes, Lucy Jean, Duncan, George and Wormstone, Ian Michael (2013) Age-related differences in signaling efficiency of human lens cells underpin differential wound healing response rates following cataract surgery. Investigative Ophthalmology & Visual Science, 54 (1). pp. 333-42. ISSN 0146-0404

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Abstract

Cataract surgery is blighted by posterior capsule opacification (PCO), which is more severe and frequent in the young than the elderly (>60 years). Our aim was to understand the biological basis for these age-related differences in PCO/wound healing rates.

Item Type: Article
Uncontrolled Keywords: adult,aging,cataract,cataract extraction,cell proliferation,cells, cultured,disease progression,enzyme-linked immunosorbent assay,fibroblast growth factors,hepatocyte growth factor,humans,interleukins,lens, crystalline,middle aged,signal transduction,wound healing
Faculty \ School: Faculty of Science > School of Biological Sciences
Depositing User: Pure Connector
Date Deposited: 28 Jan 2014 11:50
Last Modified: 25 Jul 2018 09:28
URI: https://ueaeprints.uea.ac.uk/id/eprint/47404
DOI: 10.1167/iovs.12-10425

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