Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

Springer, Jochen, Tschirner, Anika, Haghikia, Arash, von Haehling, Stephan, Lal, Hind, Grzesiak, Aleksandra, Kaschina, Elena, Palus, Sandra, Pötsch, Mareike, von Websky, Karoline, Hocher, Berthold, Latouche, Celine, Jaisser, Frederic, Morawietz, Lars, Coats, Andrew J S, Beadle, John, Argiles, Josep M, Thum, Thomas, Földes, Gabor, Doehner, Wolfram, Hilfiker-Kleiner, Denise, Force, Thomas and Anker, Stefan D (2014) Prevention of liver cancer cachexia-induced cardiac wasting and heart failure. European Heart Journal, 35 (14). pp. 932-941. ISSN 0195-668X

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Abstract

Symptoms of cancer cachexia (CC) include fatigue, shortness of breath, and impaired exercise capacity, which are also hallmark symptoms of heart failure (HF). Herein, we evaluate the effects of drugs commonly used to treat HF (bisoprolol, imidapril, spironolactone) on development of cardiac wasting, HF, and death in the rat hepatoma CC model (AH-130).

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
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Depositing User: Pure Connector
Date Deposited: 24 Jan 2014 12:44
Last Modified: 23 Aug 2018 12:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/46781
DOI: 10.1093/eurheartj/eht302

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