Activity of BAL30376 (monobactam BAL19764 + BAL29880 + clavulanate) versus Gram-negative bacteria with characterized resistance mechanisms

Livermore, David M, Mushtaq, Shazad and Warner, Marina (2010) Activity of BAL30376 (monobactam BAL19764 + BAL29880 + clavulanate) versus Gram-negative bacteria with characterized resistance mechanisms. Journal of Antimicrobial Chemotherapy, 65 (11). pp. 2382-95. ISSN 0305-7453

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Abstract

BAL30376 combines the siderophore monobactam BAL19764 (Syn/PTX 2416) with the bridged monobactam BAL29880 to inhibit AmpC enzymes and with clavulanate to inhibit extended-spectrum β-lactamases (ESBLs). We tested BAL30376 and its components versus isolates and laboratory strains of Enterobacteriaceae and non-fermenters.

Item Type: Article
Uncontrolled Keywords: anti-bacterial agents,bacterial proteins,clavulanic acid,culture media,drug resistance, bacterial,enzyme inhibitors,gram-negative bacteria,humans,microbial sensitivity tests,monobactams,beta-lactamases
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 06 Jan 2014 15:04
Last Modified: 21 Mar 2019 11:05
URI: https://ueaeprints.uea.ac.uk/id/eprint/46671
DOI: 10.1093/jac/dkq310

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