Barrett's esophagus:progression to adenocarcinoma and markers

Fang, Dianchun, Das, Kiron M, Cao, Weibiao, Malhotra, Usha, Triadafilopoulos, George, Najarian, Robert M, Hardie, Laura J, Lightdale, Charles J, Beales, Ian L P, Felix, Valter Nilton, Schneider, Paul M and Bellizzi, Andrew M (2011) Barrett's esophagus:progression to adenocarcinoma and markers. Annals of the New York Academy of Sciences, 1232. pp. 210-29. ISSN 0077-8923

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Abstract

The following on progression to adenocarcinoma and markers of Barrett's esophagus includes commentariess on the expression of claudin 4 in Barrett's adenocarcinoma; the role of acid and bile salts; the role of insulin-like growth factor; the value of reactive oxygen species; the importance of abnormal methylation; genetic alterations in stromal cells and genomic changes in the epithelial cells; the value of confocal laser endomicroscopy for the subsurface analysis of the mucosa; indications for statins as adjuvant chemotherapeutic agent; the sequence of molecular events in malignant progression in Barrett's mucosa; and the value of the macroscopic markers and of p53 mutations.

Item Type: Article
Additional Information: © 2011 New York Academy of Sciences.
Uncontrolled Keywords: adenocarcinoma,barrett esophagus,disease progression,esophageal neoplasms,humans,nadph oxidase,reverse transcriptase polymerase chain reaction,tumor markers, biological
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User: Pure Connector
Date Deposited: 16 Dec 2013 15:12
Last Modified: 25 Jul 2018 09:10
URI: https://ueaeprints.uea.ac.uk/id/eprint/45971
DOI: 10.1111/j.1749-6632.2011.06053.x

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