Pretreatment with prasugrel in non-ST-segment elevation acute coronary syndromes

Montalescot, Gilles, Bolognese, Leonardo, Dudek, Dariusz, Goldstein, Patrick, Hamm, Christian, Tanguay, Jean-Francois, ten Berg, Jurrien M, Miller, Debra L, Costigan, Timothy M, Goedicke, Jochen, Silvain, Johanne, Angioli, Paolo, Legutko, Jacek, Niethammer, Margit, Motovska, Zuzana, Jakubowski, Joseph A, Cayla, Guillaume, Visconti, Luigi Oltrona, Vicaut, Eric and Widimsky, Petr and ACCOAST Investigators (2013) Pretreatment with prasugrel in non-ST-segment elevation acute coronary syndromes. New England Journal of Medicine, 369 (11). pp. 999-1010. ISSN 1533-4406

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Abstract

Although P2Y12 antagonists are effective in patients with non-ST-segment elevation (NSTE) acute coronary syndromes, the effect of the timing of administration--before or after coronary angiography--is not known. We evaluated the effect of administering the P2Y12 antagonist prasugrel at the time of diagnosis versus administering it after the coronary angiography if percutaneous coronary intervention (PCI) was indicated.

Item Type:	Article
Uncontrolled Keywords:	double-blind method,coronary angiography,humans,percutaneous coronary intervention,aged,thiophenes,hemorrhage,piperazines,premedication,acute coronary syndrome,coronary artery bypass,purinergic p2y receptor antagonists,middle aged,myocardial infarction,female,male
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Depositing User:	Pure Connector
Date Deposited:	11 Nov 2013 13:10
Last Modified:	03 Nov 2022 15:33
URI:	https://ueaeprints.uea.ac.uk/id/eprint/44354
DOI:	10.1056/NEJMoa1308075

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