Associations of circulating retinol, vitamin E, and 1,25-dihydroxyvitamin D with prostate cancer diagnosis, stage, and grade

Gilbert, Rebecca, Metcalfe, Chris, Fraser, William D, Donovan, Jenny, Hamdy, Freddie, Neal, David E, Lane, J Athene and Martin, Richard M (2012) Associations of circulating retinol, vitamin E, and 1,25-dihydroxyvitamin D with prostate cancer diagnosis, stage, and grade. Cancer Causes & Control, 23 (11). pp. 1865-1873. ISSN 0957-5243

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Abstract

Some epidemiological studies suggest that vitamin A (retinol), vitamin E, and vitamin D (total 25-hydroxyvitamin D, 25(OH)D; 1,25-dihydroxyvitamin, 1,25(OH)(2)D) are protective against prostate cancer. However, the evidence is not conclusive, with positive and null associations reported for all three vitamins. Limitations of previous studies include small sample size, lack of population controls, and reliance on self-reported dietary intake. Few studies have explored the interactions of circulating 25(OH)D with 1,25(OH)(2)D or retinol, which are biologically plausible interactions.

Item Type: Article
Uncontrolled Keywords: case-control studies,great britain,humans,kallikreins,male,middle aged,neoplasm grading,neoplasm staging,prostate-specific antigen,prostatic neoplasms,risk assessment,risk factors,vitamin a,vitamin d,vitamin e
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Social Sciences > School of Education and Lifelong Learning
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Depositing User: Users 2731 not found.
Date Deposited: 06 Feb 2013 11:56
Last Modified: 21 Mar 2019 10:39
URI: https://ueaeprints.uea.ac.uk/id/eprint/41120
DOI: 10.1007/s10552-012-0052-5

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