Structures of Phytophthora RXLR Effector Proteins: a CONSERVED BUT ADAPTABLE FOLD UNDERPINS FUNCTIONAL DIVERSITY

Boutemy, LS, King, SRF, Win, Joe, Hughes, RK, Clarke, TA, Blumenschein, TMA, Kamoun, S and Banfield, MJ (2011) Structures of Phytophthora RXLR Effector Proteins: a CONSERVED BUT ADAPTABLE FOLD UNDERPINS FUNCTIONAL DIVERSITY. Journal of Biological Chemistry, 286 (41). pp. 35834-35842. ISSN 0021-9258

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    Abstract

    Phytopathogens deliver effector proteins inside host plant cells to promote infection. These proteins can also be sensed by the plant immune system, leading to restriction of pathogen growth. Effector genes can display signatures of positive selection and rapid evolution, presumably a consequence of their co-evolutionary arms race with plants. The molecular mechanisms underlying how effectors evolve to gain new virulence functions and/or evade the plant immune system are poorly understood. Here, we report the crystal structures of the effector domains from two oomycete RXLR proteins, Phytophthora capsici AVR3a11 and Phytophthora infestans PexRD2. Despite sharing

    Item Type: Article
    Faculty \ School: Faculty of Science > School of Chemistry
    ?? TSL ??
    Faculty of Science > School of Biological Sciences
    Related URLs:
    Depositing User: Deborah Clemitshaw
    Date Deposited: 24 Jan 2012 15:17
    Last Modified: 09 Oct 2017 15:41
    URI: https://ueaeprints.uea.ac.uk/id/eprint/36454
    DOI: 10.1074/jbc.M111.262303

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