A mild procedure for the production of secondary amines from oximes and benzisoxazoles

Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Grewal, Sukhwant S., Madeo, Fiorenza and Tsoungas, Petros G. (2003) A mild procedure for the production of secondary amines from oximes and benzisoxazoles. Tetrahedron Letters, 44 (35). pp. 6745-6747. ISSN 0040-4039

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Abstract

-2-Hydroxybenzaldoximes are reduced under mild conditions of ammonium formate/Pd-C in methanol to give secondary amines. Benzisoxazoles react under the same mild conditions to give the same products. A possible mechanism is suggested, involving the intermediacy of the benzisoxazole in the oxime conversion. (C) 2003 Elsevier Ltd. All rights reserved.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Pharmacy
UEA Research Groups:	Faculty of Science > Research Groups > Medicinal Chemistry (former - to 2017) Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021)
Depositing User:	Rachel Smith
Date Deposited:	13 Jun 2011 14:02
Last Modified:	24 Oct 2022 03:03
URI:	https://ueaeprints.uea.ac.uk/id/eprint/32132
DOI:	10.1016/s0040-4039(03)01623-x

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