Rotavirus G and P genotypes in rural Ghana

Asmah, Richard H., Green, Jon, Armah, George E., Gallimore, Chris I., Gray, Jim J., Iturriza-Gómara, Miren, Anto, Francis, Oduro, Abraham, Binka, Fred N., Brown, David W. G. and Cutts, Felicity (2001) Rotavirus G and P genotypes in rural Ghana. Journal of Clinical Microbiology, 39 (5). pp. 1981-1984. ISSN 0095-1137

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Abstract

An epidemiological study of rotavirus infection was conducted on specimens collected from patients with gastroenteritis and domiciled in the rural Upper Eastern Region of Ghana during 1998. Fifty isolates, randomly selected from 165 human group A rotavirus-positive samples, were G and P characterized by a reverse transcription (RT)-PCR assay using a seminested multiplex method. Rotaviruses of the G3 genotype were found to be the predominant strain (78%), followed by G2 (14%) and G1 (2%). Mixed infections, as shown by combinations of G3 and G2 (4%) and G3 and G1 (2%), were also observed. P typing showed P[4] (72.34%) to be the prevalent strain, followed by P[6] (21.3%), P[8] (2.13%), and a combination of P[4] and P[6] (4.3%).

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Rhiannon Harvey
Date Deposited: 19 May 2011 12:30
Last Modified: 11 Jan 2024 01:25
URI: https://ueaeprints.uea.ac.uk/id/eprint/31062
DOI: 10.1128/JCM.39.5.1981-1984.2001

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