Two derivatives of (N-phenylthioureidoalkyl)phosphonates

Checinska, L., Sieron, L., Bukowska-Strzyzewska, M., Kudzin, Z. H. and Fabian, L. (2003) Two derivatives of (N-phenylthioureidoalkyl)phosphonates. Acta Crystallographica Section C: Crystal Structure Communications, 59. O46-O50. ISSN 0108-2701

Full text not available from this repository. (Request a copy)


The structures of diphenyl [3-methyl-1-(3-phenylthioureido)butyl]phosphonate and diphenyl [2-methyl-1-(3-phenylthioureido)butyl]phosphonate, both C24H27N2O3PS, are reported. In both compounds, the thiourea moiety adopts a syn-syn conformation (i.e. the S-C-N-C torsion angles are synperiplanar), which enables N-H...O hydrogen bonds to be formed between centrosymmetrically related molecules. The geometries around the P atoms can be described as distorted tetrahedral. Some of the functional groups in each structure are disordered. The bulk of the different alkyl substituents between the amide and phosphonate groups influences the molecular conformation and crystal packing. Although the structures of these compounds and two related derivatives appear to be similar, they are not isostructural.

Item Type: Article
Uncontrolled Keywords: o-diphenyl,o
Faculty \ School: Faculty of Science > School of Pharmacy
University of East Anglia > Faculty of Science > Research Groups > Drug Delivery and Pharmaceutical Materials
Depositing User: Rachel Smith
Date Deposited: 19 May 2011 11:01
Last Modified: 25 Jul 2018 07:04
DOI: 10.1107/s0108270102021820

Actions (login required)

View Item