Adiponectin resistance in heart failure and the emerging pattern of metabolic failure in chronic heart failure

Springer, Jochen, Anker, Stefan D. and Doehner, Wolfram (2010) Adiponectin resistance in heart failure and the emerging pattern of metabolic failure in chronic heart failure. Circulation: Heart Failure, 3 (2). pp. 181-182. ISSN 1941-3289

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Abstract

In recent years, an interesting shift in our understanding of chronic heart failure (CHF) pathophysiology may be observed. Beyond the traditional concepts of hemodynamic failure and neuroendocrine activation, it is increasingly appreciated that CHF is a much more complex and truly systemic disease including the peripheral organs and whole body regulatory processes as well. Novel concepts such as the systemic inflammatory immune activation and the skeletal muscle hypothesis have emerged.1 These concepts recognize the significant contribution of peripheral changes to symptomatic status, disease progression, and outcome in CHF.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User:	Rhiannon Harvey
Date Deposited:	06 May 2011 08:16
Last Modified:	15 Dec 2022 01:28
URI:	https://ueaeprints.uea.ac.uk/id/eprint/29965
DOI:	10.1161/CIRCHEARTFAILURE.110.945063

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