Transmission events within outbreaks of gastroenteritis determined through analysis of nucleotide sequences of the P2 domain of genogroup II noroviruses

Xerry, Jacqueline, Gallimore, Chris I., Iturriza-Gómara, Miren, Allen, David J. and Gray, Jim J. (2008) Transmission events within outbreaks of gastroenteritis determined through analysis of nucleotide sequences of the P2 domain of genogroup II noroviruses. Journal of Clinical Microbiology, 46 (3). pp. 947-953. ISSN 0095-1137

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Abstract

Tracking the spread of noroviruses during outbreaks of gastroenteritis is hampered by the lack of sequence diversity in those regions of the genome chosen for virus detection and characterization. Sequence analysis of regions of the genes encoding the RNA-dependent RNA polymerase and the S domain of the capsid does not provide sufficient discrimination between genotypically related strains of different outbreaks. However, analysis of sequences derived from the region encoding the P2 domain showed 100% similarity among strains from the same outbreak and

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User:	Rhiannon Harvey
Date Deposited:	28 Apr 2011 14:59
Last Modified:	11 Jan 2024 01:22
URI:	https://ueaeprints.uea.ac.uk/id/eprint/29853
DOI:	10.1128/JCM.02240-07

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