Expedient synthesis of substituted (S)-N-(α-methylbenzyl)aziridines

Bew, S.P., Hughes, D.L., Savic, V., Soapi, K.M. and Wilson, M.A. (2006) Expedient synthesis of substituted (S)-N-(α-methylbenzyl)aziridines. Chemical Communications (33). pp. 3513-3515. ISSN 1359-7345

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Abstract

We report for the first time that after O-acylation the conjugate addition products of (S)-N-(α-methylbenzyl)hydroxylamine undergo an efficient diastereoselective 3-exo-tet ring-closure reaction affording 2- and 2,3-disubstituted-N-alkylaziridines in good to excellent yields. © The Royal Society of Chemistry 2006.

Item Type: Article
Faculty \ School: Faculty of Science > School of Chemistry
University of East Anglia > Faculty of Science > Research Groups > Synthetic Chemistry
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Depositing User: Rachel Smith
Date Deposited: 15 Feb 2011 10:03
Last Modified: 25 Jul 2018 06:04
URI: https://ueaeprints.uea.ac.uk/id/eprint/21370
DOI: 10.1039/b606033a

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